Select Committee on Health Minutes of Evidence



Examination of witnesses (Questions 320 - 339)

THURSDAY 9 DECEMBER 1999

PROFESSOR JOHN BRITTON, DR JENNY MINDELL, SIR ALEXANDER MACARA and DR BILL O'NEILL

Mr Austin

  320. I was at a meeting a few nights ago where one of the physicians was saying that the incidence of heart disease was significantly increased by environmental tobacco smoke and I see you left that off your list.
  (Professor Britton) There is a long list of diseases associated with that and I have mentioned some of them and heart disease is another.

Audrey Wise

  321. What do you think of the tobacco company's approach to medical science both over the last few decades and currently?
  (Sir Alexander Macara) They have been very flattering, have they not? All the evidence now is that they were at pains to repeat the work which had been done by independent scientist; in fact, they employed other independent scientists to research the effects of tobacco. The evidence now is that their own research has confirmed the evidence which had been produced and then they appear to have been at pains, as we now know, to conceal this confirmation. You may say that they were highly flattering in that they recognised the need to repeat the work no doubt hoping to be able to find loose threads that they can pull to unravel the whole fabric of the argument against them. I am afraid in historical terms they have shot themselves in the foot because they have now been revealed to have been responsible for deliberate suppression of the facts and misrepresentation about the facts which had been produced.

  322. I am interested in some of your phases you have used, such as "as we now know" and "have now been revealed" and that would not have happened to the same extent by any means without people rooting about in dusty archives. I wonder if you would care to comment a little bit more on that because I have noticed in the BMA evidence you have a list of tobacco company's failures, that is failure to inform of the dangers of smoking and failure to reduce the harmfulness and failure to disclose the contents and so on. Failure is an interesting word in that context because failure suggests you have tried to do something and you have not quite managed it. I would rather say that they have tried to mislead rather than failed to inform and I wonder if you would care to comment on the thrust of your evidence there. Is your own evidence strong enough? We hear that governments are weak.
  (Sir Alexander Macara) We do not hesitate to use pretty strong language on occasions because we feel it is our public duty to promote public health and to protect our patients, but sometimes we want to assume that there might just be some intention of good faith on the part of the tobacco manufacturers. It may be that they felt their responsibility was to protect their markets and their shareholders and their employees, which is a very worthy matter if you are an employer or a shareholder out with the responsibilities to the public health. They might have thought that was your responsibility as Parliamentarians and ours as medical scientists. We were restrained in the use of that word(failure), but I certainly would not disagree with the view that it is hardly strong enough.

  323. You have mentioned your disappointment at the failure of people to act on warnings about health damage. It does seem rather remarkable that there has been quite a lot of knowledge and suspicion about damage to health. I wonder if you would care to reflect and discuss the issue of the public mood in connection with this. We went to the USA last week and I picked up a very strong feeling of anger which is missing here. People are warned and there is a certain amount of anger on the issue of the rights of the non-smoker, but because of the disclosure of the tobacco companies misleading and manipulating people in the USA and ripping off and denial and lying there is a considerable mood of public anger. Do you not think that if people become angry about being manipulated they may be more open to public health messages?
  (Dr O'Neill) The reality is that in this country it is estimated that we have been spending about £10 million per year getting across the health message as opposed to probably ten times that amount of money being spent by the industry. There is no doubt that in the United States the series of cases that have gone to the courts has done an enormous amount to highlight the dangers associated with smoking and, in particular, to highlight the behaviour of the industry. The British Medical Association publicly supported the group action that has been taken on behalf of the 52 patients with lung cancer in this country through the courts, not because of the probably relatively paltry sums of money that patients were going to get at the end of the day, but because of the information that would be disclosed in court, because for the first time the truth would see the light of day and we certainly regretted the collapse of that case.

  324. I think some of us individually might agree with you on that. Does that not make it even more important to ensure that the truth sees the light of day?
  (Dr O'Neill) We believe that until the industry are put in the dock in this country, whether it be in front of a Committee such as this or some other forum, we will not have the full truth, and nor will the public, of what has actually gone on over the last 20 to 40 years.

  325. The Chairman asked you whether you had attempted to access the Guildford depository. Are you aware that if you did try tomorrow you would almost certainly be told, "I am sorry, nobody can get in for at least the next four months because we are booked up"?
  (Dr O'Neill) We are absolutely aware of that.

  326. Perhaps there is some merit in looking in dusty archives. If they are so keen on keeping it secret, should not all of us be rather keen on getting it revealed?
  (Professor Britton) I would not wish to be misinterpreted—

Chairman

  327. I think you might have been, Professor.
  (Professor Britton) On the one hand it is important to establish the truth of events that have gone by if that influences public mood in terms of engendering a sense which I, too, have detected in the United States of betrayal by an industry, but the facts of the health arguments have been with us for nearly 40 years and perhaps it is appropriate to look to the future rather than the past in terms of resolving this problem.

Audrey Wise

  328. But that implies, does it not, that they have all changed their spots?
  (Professor Britton) Who has?

  329. The tobacco companies.
  (Professor Britton) Effective public health measures to do with smoking will come from legislation.

  330. Are you conscious of the scientific and technological precision and power which we and health authorities in general are facing? We were told, for example, by the US Food and Drug Administration that the scientific knowledge and technological power of the tobacco companies enables them to ensure a nicotine dosage of such precision in every cigarette packet that outweighs the capacity of the pharmaceutical companies to ensure the dosage they want in nicotine replacement therapy. That is the level of scientific and technological power that we are facing. Does that suggest that this is all to do with past attitudes of the tobacco companies?
  (Professor Britton) Tobacco companies produce very sophisticated products, I do not think anybody here would argue against that. Cigarettes are nicotine delivery devices, that is what they are created to be. Salbutamol inhalers are broncho-dilatory devices used by people with asthma to treat their asthma. They are also very sophisticated devices. The asthma device is legislated to very tight standards of safety and disclosure and cigarettes are not. That is a failure of legislation, not of technological advance.
  (Sir Alexander Macara) It is even worse than that because we have evidence of the manufacturers deliberately putting additives about which we simply do not know enough into tobacco in order to increase the absorption of nicotine from the bronchi. They even use chocolate for this purpose. I have no doubt if they put on the packet that their product contained chocolate it might be a very clever marketing device. I think they ought to have me as a consultant. They put it there in order to increase the absorption of the nicotine in the cigarettes. That is absolutely right, they are using the results of their own research to potentiate the addictive part of their product.

  331. That does suggest that when we talk about manipulation by the tobacco companies it is current as well as past.
  (Sir Alexander Macara) There is no question about that. I do not know whether my colleagues would like to add anything.
  (Dr Mindell) I think what Professor Britton was saying is that if governments want to act to introduce comprehensive legislation to control tobacco they can do that on the basis of what is already known without necessarily having additional information from the archives. However, the archive material is important partly because of increasing the public's awareness and acceptance and demand for such legislation but also to avoid the tobacco industry knowing things that Government does not when the legislation is worded and that is why I think that continuing exposure of current research and other internal memos would be important as well.

  332. I am very anxious that Professor Britton should not be misinterpreted by anybody else.
  (Sir Alexander Macara) So are we.

  333. We had an exchange with the Department of Health on this when they came to give evidence and some of us were surprised to find that there is no assessment of the real public health consequences made about additives, additives just get approved. We were told, "Well, we don't look at whether they are dangerous because they are used in such small quantities". I did point out that the purpose of some of them was to make the tobacco more palatable and more attractive. You could use an analogy with cocaine: you use spices and salt in very small quantities, but it has a very big effect on whether you want to eat it or not and the same thing could apply to cigarettes. It may be that this message goes into the Department of Health. Would you like to add your comments on this particular aspect?
  (Sir Alexander Macara) Dr O'Neill certainly will. I would just add that strychnine is very effective even in the very smallest possible doses.

Dr Brand

  334. Are you suggesting that we add that to tobacco and shorten the course of events?
  (Sir Alexander Macara) I can think of some people who might think of it as an advantage.
  (Dr O'Neill) The reality is that we regulate our food, we regulate our drugs and tobacco does not fall into either category. The majority of additives in food are regulated. There is absolutely no reason why additives in tobacco and other constituents in tobacco should not be regulated and until we have effective regulation we are unlikely to see any real change.

  335. Can I pick up that point on regulation, Mr Chairman, because we put the same point to the Department of Health, which is that there does not seem to be any consumer protection for people that smoke. The feedback I think we had was, "Well, why should there be since it is such a nasty habit anyway which kills half its consumers", and I think there has been an absolutist attitude towards smokers which is beginning to shift a little. I recognise in the evidence we have received from ASH and in the written evidence from the Royal College of Physicians that people are now talking about safer cigarettes and the regulation of products. I do not want to be too historical, but have we not been at fault in saying that we really cannot cope with anyone that smokes at any time?
  (Dr Mindell) I will make two points in response to that. Firstly, as regards regulation, we have the bizarre situation at the moment that nicotine delivery devices that deliver only nicotine are highly regulated, but if they deliver thousands of other toxic chemicals as well then they are not regulated. You should remember that almost all smokers start smoking when they are children, when they are far too young to be concerned with dying when they are 40 or 50 rather than when they are 60 or 80. Most smokers want to give up but they are addicted. When you interview teenagers you find that most of them say, "Yes, I smoke now but I'm going to stop", and they find it very difficult to do so. Some find it extremely difficult. Some have managed to stop. We know that there are still a very large number of people who would like to stop smoking. There are a lot of inequalities in this country, not so much in who starts smoking and not so much in who wants to stop, but particularly in those who succeed in stopping smoking and that is where the biggest divide is.

Chairman

  336. So it is a social class divide, the implication being it is middle class people who can stop and working class people who cannot, is it?
  (Dr Mindell) Those in the poorest circumstances may not be able to afford the additional benefit of nicotine replacement or they may have so many other stresses in their life that the difficulties of stopping smoking are more than they feel they can cope with. The two most important things in stopping smoking are the desire to want to stop and to believe that you can stop and that you can exist without cigarettes and this is why all these other things that we have also been touching on, whether it is price rises or smoke free areas, are also important for smoking cessation because it can encourage people to exist as a non-smoker.

Dr Brand

  337. Is it not very important that we have access to the information that clearly the tobacco companies have to their knowledge that allows them to produce products that encourage people to continue?
  (Professor Britton) It is clearly important to know what is in cigarettes. The gains in public health that are to be realised have to do with legislating against what is there and what is likely to be produced in response to legislation. A point one of my colleagues made was that having a fuller awareness of what is known about tobacco technology is crucial to the phrasing of such legislation and the formulation of legislation, but the public health gains can be made without getting too obsessed with what is actually in the cigarette.

Mr Austin

  338. Can I deal with what is in the cigarette. In a previous session, we had evidence that suggested that a large number of smokers actually believe that smoking low-tar cigarettes or lights or milds or ultra-lights are less harmful, but we have had evidence that because they need to get their fix, they engage in compensatory smoking, so that more virulent forms of cancer and adenocarcinomas have been increasing as well, which brings me on to whether there is such a thing as a safer or a less deadly cigarette. Obviously the Government's health campaign is that obviously, we all agree, the best thing is not to start and if you do start, to stop, but even if the Government meets its targets of getting people to quit smoking, in ten years' time a quarter of all adults will still be smoking and overwhelmingly in the poorest groups in society. Is it possible to reduce that health impact on those who continue to smoke by requiring, by legislation, changes to the content of cigarettes, to remove selectively or reduce chemicals which we know contribute to cancer and lung and heart disease?
  (Sir Alexander Macara) It would be one contributory factor, but on its own it would be of limited value.
  (Professor Britton) I think there are at least two issues raised by that. One is genuine harm reduction in smokers who cannot give up and that is obviously as desirable as any other harm reduction intervention. One of the problems, as I see it, with the whole low tar strategy is that what it may well do is encourage people to continue smoking, believing that they are smoking a safer product, when in fact they are not. I think it is a very difficult judgment to make between something that genuinely reduces harm for those people addicted to the products and who cannot give up from that product which actually increases harm by extending the market for the product.
  (Sir Alexander Macara) There is no such thing as a safer cigarette; there are only less dangerous cigarettes.
  (Dr O'Neill) I think we need to be very careful with the terminology because there is no doubt about it, that the industry has scored an enormous goal with the concept of low-tar and light cigarettes. I think we need to make sure that that does not happen again. Having said that, I think we do need to acknowledge the fact that even if we meet the targets which are set, 24 per cent of the population will still be smoking in ten years' time, and whatever can be done to lessen the burden of disease in that group of people clearly is very important, but absolutely accepting the point that Professor Britton made, that we need to be careful that that then does not fudge the whole issue, that we do not find we are actually discouraging people from giving up cigarettes by implying that there actually is a safe product. It is quite clear that there cannot be a safe product in the way in which we understand this product. There are clearly opportunities for looking both at additives, for looking at other constituents in cigarettes, and you have already had evidence about the possibility of lowering nitrosamines in cigarettes and lowering carbon monoxide levels in cigarettes which would respectively have an effect on the burden of cancer and indeed heart disease. I think those avenues should be pursued, but I think we need to make sure that we are actually getting at the truth we have all of the information and that we do not allow the industry further opportunities to score points on this issue.
  (Sir Alexander Macara) And we do not allow the industry to try to paint those of us who are anxious to help the victims of their successful marketing, that we do not allow them to paint us as nannies or as health fascists because this is the obvious ploy now which I think in part answers Dr Brand's question as to why are we not doing enough to protect smokers. I sense, Chairman, and I am sad to say this, but I sense with your colleagues, within government generally, within the Department of Health a terror about being accused of being nannies or health fascists when all we are trying to do is the job you have been elected to do and we have a moral duty to do which is to stop these people from killing people to the extent that we possibly can.

  Chairman: I think I will bring Simon Burns in and he is not called "Burns" for nothing!

Mr Burns

  339. If there is no such thing as a safer cigarette, but there are only less dangerous cigarettes, then how much do you think that nitrosamine-free cigarettes are less dangerous than conventional cigarettes?
  (Professor Britton) In theory, nitrosamine-free or nitrosamine-reduced cigarettes should be safer than conventional cigarettes, but I think that there is a risk with initiatives such as that, as with the low tar initiative which dates back 30 years, to assume that because it seems logical that something will generate a health gain, it actually will. What we have seen with low-tar cigarettes is a change in the way that people smoke, the products that they smoke and a change in the disease profile that emerges from it, so the assumption that reducing tar will produce a health benefit may have actually backfired by just changing the profiles of cancers caused and by people compensating and finding a way around the measures that have been made to reduce the toxicity of the cigarette, so, in theory, yes, reducing nitrosamines, reducing tar in general should help, but, in practice, you do not know it does until you have introduced it and tried it, and if that perpetuates smoking in society for another 30 years while you decide whether it has worked or not, you have lost.


 
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