Select Committee on Science and Technology Minutes of Evidence


Examination of Witnesses (Questions 740 - 751)

WEDNESDAY 15 SEPTEMBER 2004

REV DR JOHN I. FLEMING, RT REV DR MICHAEL NAZIR-ALI, MRS JOSEPHINE QUINTAVALLE AND DR HELEN WATT

  Q740  Bob Spink: Comparing the designer matching embryos and the cord blood storage solutions to curing sick children, which do you think is a better solution?

  Mrs Quintavalle: From my perspective, obviously, I am very interested, and one of the recommendations I brought on my little list of points today is to say I would like to see much greater investment in cord blood storage and research. I found material as long ago as 2001 from a body in Newcastle doing research in this area, showing extraordinary results from a massive national banking of cord blood. We could avoid the whole issue of the designer baby. CORE likes to look for very pragmatic responses to ethical dilemmas, and I think this is the pragmatic response. It would be a service available to everybody and not to a select few.

  Q741  Dr Harris: Did nature intend that cord blood be stored?

  Mrs Quintavalle: I have no idea, Evan, and going back to a question you asked me earlier, I am not saying that man should not be making efforts to cure disease and putting babies in incubators and doing things to help. I think though that we draw the line at some things. For example, I do not harvest organs from street children in Brazil because nobody wants them. It is where we draw the lines that ethics is about. Nature gave man the brains to understand, and we realise that the cord blood stem cells are very, very valuable commodities, and I think we should be harvesting more.

  Q742  Dr Iddon: Dr Watt, in your evidence you suggest that freezing of embryos should be prohibited. I would like to know your reasoning for that because the evidence we save received suggests that even though a frozen embryo may lose some cells, that does not seem to affect the health of any baby born of the new medical technologies. Do you know something that the medical community does not know?

  Dr Watt: Our point about freezing was that if you did not create excess embryos, you would not need to freeze. It is not that I am as against freezing as an emergency response to leave particular embryos, but you should not be creating excess embryos in the first place. In terms of the risks of freezing, the risks to the embryo are significant, particularly if the embryo has been subjected to embryo biopsy before freezing, in which case they are even higher. Risks to born children—

  Q743  Dr Iddon: Is there any evidence for that? You are suggesting that children born are damaged—

  Dr Watt: What I am saying is that embryos are killed by freezing, even if you are trying to freeze them to save their lives, and there is a lot of evidence that this is not a healthy process for the embryo.

  Mrs Quintavalle: There definitely is evidence, which we submitted in our court case. The biopsied frozen embryo has much less likelihood of surviving freezing than the embryo that has not been biopsied, and that is statistical evidence, which I am very pleased to provide the Committee with. Like Helen, I do not think we should be creating surplus embryos, but I would like to draw the Committee's attention to the fact that it appears that within the NHS provision of IVF, embryo freezing is not being offered routinely. I will submit to you afterwards a document that is going to be published in human reproduction, with Alison Murdoch as one of the signatories, and it is on embryo donation and egg donation. It points out that the NHS patients at the Newcastle infertility centre are not provided with freezing for their embryos, and I find this very worrying. It is a very big conflict of interest that the NHS patient is not being offered this provision for the surplus embryos that are created.

  Q744  Dr Iddon: I just want to clear up a point from the previous discussion on the psychological effects on a child born from these procedures. Obviously, children brought up in many families suffer psychological damage because of the family circumstances. Is that any different than what we were discussing earlier?

  Dr Watt: The question is, do we create these circumstances? Obviously, some children are orphaned and so on and you cannot prevent some things happening, but do you deliberately create children in circumstances that you know carry at the very least risks to those children?

  Q745  Dr Iddon: Families are creating circumstances all the time that do psychological damage in children.

  Dr Watt: As Father Fleming was saying, I am not recommending other forms of conception, for example by men who do not intend to look after their children naturally conceived, and I am not defending it in the natural case any more than in the case of sperm donation.

  Rev Dr Fleming: I draw your attention to the SPUC document we have given you, which has a fair amount of material on frozen embryos, relying on the data from Australia from the Infertility Treatment Authority. When it comes to the transfer of fresh embryos, 9.5% of embryos transferred fresh survived to be born alive. In the case of embryos that were frozen and then thawed, 3.1% of embryos transferred after freeze/thaw, survived and were born alive. It is beyond doubt that freezing as a process has attended with it significant increased wastage and lack of capacity to survive. Even if they survive the freeze/thaw process, they are less likely to implant than a fresh embryo, which is why I think all the IVF doctors I know today would prefer to be transferring fresh embryos and preferably one rather than three.

  Q746  Mr McWalter: Obviously, the role of this Committee is to take evidence and take your evidence and weigh it in the balance with a lot of other evidence. Suppose it turned out that we take evidence saying that IVF babies are particularly unhappy or whatever, or the example just given about embryo freezing being highly detrimental to the health of the embryo and so on, but when we weigh it in the balance we find out that the overall balance of evidence is, as it were, against you, you still would not want us to go down the pathway of giving the HFEA the green light, would you, because even if the evidence was against you, you still believe that the moral case determines the issue in and of itself?

  Rev Dr Fleming: It is a fair question.

  Q747  Mr McWalter: Would that be a fair description of your position, so that the stuff about evidence is really ancillary to that moral argument?

  Rev Dr Fleming: It is a "yes" and "no". I have accepted, and SPUC has accepted that IVF and other technologies are practised in Britain and are likely to go on being practised in Britain. We are not calling for the outlawing of them in principle. We are saying that there are some matters attendant upon the current practice relating to reproductive technology that parliament could and should take action to avoid. That is very different. If the evidence indicates—and you are welcome to check the sources that I have richly given you here—that there is good evidence that harm is done, then clearly I would imagine that, as elected representatives, you would want to say, "okay, IVF is going to continue, but are there things we need to do to reduce harm to the woman, reduce harm to the couple and reduce harm to the child?"

  Q748  Mr McWalter: Your position is that it is actually an intense moral wrong; it just so happens that not all moral wrongs are not proscribed by law.

  Rev Dr Fleming: Exactly, like adultery is a great moral wrong, but I am not proposing that you make it illegal.

  Q749  Mr McWalter: Michael, your position is significantly different from the others, in terms of the ethical position. The SPUC position is that there is a class of persons, and it includes four-cell embryos, whereas your position is that at very early stages a group of cells or zygote or embryo or whatever has only a degree of membership of the class of persons. Is that a fair description of what you said earlier? If that is so, there is a strong epistemological difference between you and the others, and hence a very strong ethical difference potentially as well. You might, a result, not agree that ethics plays as intense a role as the others do who are on this panel today.

  Rt Rev Dr Nazir-Ali: Intensity is a subjective matter, a matter of how you feel. I am saying that throughout much of Christian history there has been an incremental view of personhood that emerges gradually. But there has also always been the view that the embryo is the potential from which the person emerges, and therefore is worthy of respect.

  Q750  Mr McWalter: That is uncontested by all parties.

  Rt Rev Dr Nazir-Ali: That is right. What we do not know of course, and perhaps can never know, is when exactly there is a human person. So while I would not dogmatically say there is a human person at conception or at the three or four-cell stage or whatever, I would say that the precautionary principle has to be exercised here because we know that this something from which the person comes, whenever that happens. The law recognises this precautionary principle in its present form—the 14-day limit. The debate is, how far back to conception you extend that precautionary limit. I suppose if there was a discussion between us, that it would be about how far back you extend the precautionary principle.

  Q751  Mr McWalter: What I want to draw out is the fact that because you do not believe that, as it were, this matter is determined by the moral imperative—although obviously your position has a very strong moral component—for you the role of statistical and other evidence is much more significant in coming to an overall decision about how we are going to manage these things within our legal structure. Would that be a fair description?

  Rt Rev Dr Nazir-Ali: Absolutely, and one comes to a moral position by looking at the evidence; and the moral position is not independent of evidence.

  Chairman: We have other business to attend to now, which is a shame because we could have gone on for hours. We can write and ask you if there are any further questions. Thank you very much for coming and being frank, open and honest. It has been extremely helpful for the Committee's judgment, and will be reflected, I am quite sure, in the final document we produce. We have some way to go yet and have to talk to other people, but it is progressing. Thank you very much for helping.





 
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