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22 Nov 2007 : Column 1354

The scientific advisory group is modelling for an extremely effective countermeasures strategy, but within that there is not just a 50 per cent. antiviral stockpile, but a 75 per cent. antiviral stockpile. Although the Secretary of State says that he is not at the moment making any proposal for a pre-pandemic vaccine, the countermeasures contemplated in that model by the scientific advisory group include a 100 per cent. pre-pandemic vaccination. So will he undertake to consider in those discussions whether that is a viable model to allow further countermeasures to be put in place?

On a pre-pandemic vaccine, the 3.3 million doses of H5N1 that we have in hand were bought not only for possible use with health care workers, but for research. The Secretary of State knows that he cannot explain why they have not been used for any research, but research into H5N1, other vaccines and, indeed, vaccine technology is a vital part of our long-term preparations. Even if a pandemic does not occur in the next year or two or three—if it is 10 years hence—the efforts that we take now to improve vaccine technology so that we have cell-based or even DNA vaccines to respond much more quickly to a pandemic could be something for which we will be extraordinarily grateful in future.

The Secretary of State is still buying antivirals on the basis of treatment only. Will he undertake further to consider prophylaxis, particularly household prophylaxis, for antivirals and the acquisition of a stockpile for that purpose? Will he tell the House whether he has considered the threat of resistance developing to Tamiflu and whether he contemplates any subsidiary stockpile of Relenza, for example, for that purpose?

The framework document is very limited in its response on critical care beds. It is quite clear from work done by the Intensive Care Society two years ago that our critical care capacity will be overwhelmed in the event of a pandemic. It called for a doubling or a tripling of critical care capacity. What steps has the Secretary of State already put in place to expand critical care?

On school closures, the framework still pretty much says, “We’ll see where we get to, and then the Government will issue advice.” Did not Operation Winter Willow, if it was realistic, suggest that the Government will not be in a position to decide whether schools close in a severe pandemic? Parents will keep their children at home. Schools will close. Large numbers of health care workers and others will be at home, looking after their children. We must have a strategy in place that understands human behaviour in circumstances where the pandemic is severe.

Are the Government considering following the example set by the American Government of having not only WHO alert status, but their own view of the relative severity of a pandemic to guide the selection of countermeasures? It is certainly true that schools in America have already sent guidance to parents about what would happen at their school in the event of a pandemic.

I am sure that what the Secretary of State said about the WHO and developing countries is very welcome, but he will know, and the House should understand, that if there is a pandemic with a high case fatality rate and as many millions of people in developing countries are immune-compromised as a result of HIV/AIDS, the
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potential threat worldwide is dramatic. So it is increasingly important that, for example, the Department for International Development and the Department of Health jointly work on trying to support contingency planning and countermeasures in some of those developing countries.

People often say, “We had BSE. We had SARS. We’ve had one scare after another. Isn’t this just another scare?” Frankly, it has never been my view, as the Secretary of State knows, that this is just another scare. We had three pandemics in the last century. The characteristics of this one, with H5N1 persisting in the bird population alongside large numbers of humans, are probably more like those of 1918. The case fatality rate in 1918 was 2.5 per cent. This is a severe pandemic. It might not happen in the next few years, but it will happen at some point. Therefore, the measures that we take, as an insurance premium, remain modest in relation to the dreadful consequences of suffering from a pandemic on that scale, without those countermeasures being in place.

I have no doubt that Britain remains among those who are best equipped and have some of the best planning in place, but so we should be. I hope that we will be an exemplar to other countries, both in how we respond here to a pandemic and in how we support others, particularly the least developed countries.

Alan Johnson: I very much welcome the hon. Gentleman’s constructive remarks. To pick up some of the issues, first, my right hon. Friend the Minister of State, Department for Transport said, when a Health Minister, that we would have a report ready in January. In essence, having the framework available now has allowed us to take full cognisance of Operation Winter Willow and to take into account the responses, because we had a closing date of 16 May for people to respond to the lessons that were learned. So the framework is better for the short delay.

The hon. Gentleman asks about the amount being spent, but may I give a hazard warning? I am perfectly willing to answer all questions on how much we spend on antivirals, antibiotics and so on after we have clinched a deal. The problem with our talking about the amount that we plan to spend is that it hampers our ability to get a good commercial deal. I can tell the hon. Gentleman that the advance supply agreements, for instance, cost £155.4 million over four years and the amount that we spent on H5N1 was £33.4 million, but I am reluctant to give the global figures for the stocks that we are due to negotiate on.

The hon. Gentleman mentions the scientific advisory group’s option about 75 per cent. coverage. He is absolutely right that that was an option. The question is whether that is a viable model, and the scientists are still discussing the answer and whether we can use the antiviral for prophylaxis, because that very important issue is still subject to emerging science.

The hon. Gentleman makes an important point about using H5N1 vaccine for research. He knows that I said in a frank piece of correspondence with him earlier this year that I did not know why it was not being used for research, but we can discuss why we cannot use that for greater research when we have the scientists in front of us.


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Work is going on to look at Relenza, because of some evidence that people might become resistant to Tamiflu and because it is advisable to have two drugs available. At the moment, Tamiflu is the only one.

On critical care capacity, when the hon. Gentleman sees the surge capacity guidance, he will realise that we spend a great deal of time considering how we can deal cost-effectively with a surge that is likely to arise from a pandemic, and critical care is obviously a factor of that.

On school closures, I had some wise advice from my right hon. Friend the Member for Blackburn (Mr. Straw), who told me that when he was at school in 1957, during the Asian flu outbreak, the school was closed down. It is good to have such distinguished, wise and elderly colleagues in Cabinet to tell us about such things. Essentially, we believe that the best thing that can possibly happen is that anyone who has symptoms of pandemic flu goes home and stays there; they should not go anywhere where they might spread it. That is why we now say in the guidance that there has been a change in the assessment programme for antiviral access, for instance, for children under seven. Previously, the guidance said that they should be initially seen by a GP. We now think that we can deal with that through the national flu line service, thus avoiding parents having to take ill children to doctors’ surgeries, where we could get a greater spread.

The other very important point that the hon. Gentleman makes is about the need for international co-operation, particularly in relation to HIV/AIDS and having DFID, the Foreign and Commonwealth Office and our Department working together. We do that through the WHO, and it is a very important part of the partnership approach to the issue.

Finally, the hon. Gentleman is absolutely right in saying that this is not another scare. It is very important to reassure the public that we are not making this statement on the framework because there is an impending outbreak of pandemic flu; we are doing so because there were no national plans in 1968 for Hong Kong flu, which was the last outbreak, when we just fudged everything and got through as best we could. We need to have these plans. The hon. Gentleman is right that there will be an outbreak of pandemic flu—it is not a question of if, but a question of when—and it is right that this country is properly prepared.

Norman Lamb (North Norfolk) (LD): I am grateful to the Secretary of State for his early contact today to alert me to the statement and for early sight of the statement itself. He and the Minister responsible for public health have my reassurance that I am keen to co-operate fully on the process and look forward to hearing further about arrangements to meet with scientists and so on.

The statement comes just a fortnight after the outbreak of avian flu in my part of the world, in Suffolk. I fully understand that, as the Secretary of State made clear, there is not any fear of an imminent outbreak, but I guess that he would agree that we have been given a timely reminder of the absolute importance of getting a robust framework in place without delay.

On capacity in the NHS and social care, we talked yesterday about occupancy rates with regard to hospital-acquired infections. Is a system that is under quite a lot
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of strain in terms of capacity, in relation to both health and social care, in a state to cope with a pandemic flu outbreak? Is there a need to look further at whether to increase capacity in the NHS and social care?

On international action, I note that the Secretary of State made it clear that the UK is ahead of the game. That is good to hear. However, presumably it is important, in terms of our own interests, quite apart from the interests of others, to promote effective action across Europe—quite apart from globally. What co-ordinating work is taking place with other European countries to ensure that they get their plans in place effectively? A report from the WHO found that less than half of the EU countries surveyed provided defined plans for the distribution of antivirals or specific guidance on where vaccines would be stored, how they would be distributed and who would administer them. Two thirds of national plans depart from WHO guidelines on the crucial step of limiting people’s movements from affected to unaffected areas. What is the Secretary of State doing to ensure that the whole of Europe responds effectively and in accordance with WHO guidelines?

In December 2005, the House of Lords Science and Technology Committee issued a report that questioned whether the Department of Health could provide strong enough leadership in the event of a flu pandemic. It recommended the appointment of a Cabinet-level Minister, who would be responsible for co-ordinating implementation of a framework plan if there was a pandemic. Has that been considered, or is it under consideration currently? Is the Secretary of State happy that there is sufficient co-ordination with other Departments, and also, critically, with local government and public agencies? Reference has been made to the provision of resources to help the planning process. Does local government have sufficient resources to plan effectively in co-ordination with national Government?

Finally, on the time scale, can the Secretary of State give some indication of when the meetings in which the Conservative spokesman and I are to be involved are likely to take place, and when he hopes to get a final framework in place? We are all agreed that that is of the utmost importance and we all have a shared objective to get it in place as soon as possible.

Alan Johnson: I thank the hon. Gentleman for his constructive approach to the issue. He mentioned H5N1 in Norfolk. I know that he knows the medical advice, but it is probably as well if I read into the record the fact that H5N1 is predominantly an infectious disease of birds and that there is very little evidence of widespread human infection thus far, just as there is very little evidence of the kind of easy person-to-person transmission required to cause a human flu pandemic. However, H5N1 is a potential seedbed for the emergence of such a virus, which is why poultry workers in his constituency have been given the vaccine for H5N1 and offered regular seasonal flu jabs.

The hon. Gentleman asked whether the NHS will be able to cope. Yes, we are sure that it will. It will be able to cope much better for having gone through the national simulation project, Winter Willow, earlier in the year. We keep the situation constantly under review. The NHS showed its capacity to respond in relation to
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events such as the floods in Gloucester and my area recently. The situation, once the pandemic strikes, will of course be on a far bigger scale. However, all the evidence is that the NHS is ready to step up to the mark in these situations.

The hon. Gentleman asked about effective action across the EU. He is right that there is a necessity for that. The Minister of State, my right hon. Friend the Member for Bristol, South, hosted a conference in July of other European member states, and there was a discussion through the WHO in Washington recently, which included most European Union member states. We are all interdependent in the European Union, which is an important reason why the EU can give a focus to dealing with a pandemic. If the EU did not exist, we could not have that kind of cross-country co-operation.

The co-ordination in this country would take place through Cobra, chaired by the Prime Minister. The hon. Gentleman asked about co-ordination with public agencies. Gold command was another example of public agencies working together very well, in terms of both the security threat and the recent floods. I have absolutely no doubt that public agencies will be able to cope in the event of a flu pandemic.

Finally, the hon. Gentleman asked when we should have the meeting with my right hon. Friend the Minister of State and the experts and scientists. That should take place as soon as possible. I was talking to the hon. Member for South Cambridgeshire earlier. Perhaps we should organise a Hansard Society debate on the issue so that we can have all the available experts participating, as well as having important debates in the Chamber.

Dr. Howard Stoate (Dartford) (Lab): I thank the Secretary of State for an excellent statement. I am sure that the entire country will be pleased to hear that not only is Britain more prepared than any other country in Europe, but we are more prepared than we ever have been. The most effective and likely way of dealing with pandemic flu is the development of an effective vaccine. There are two problems with that. First, we have to develop the vaccine when we have the virus, and therefore we cannot do it yet. The second big problem is capacity for production. The biggest bottleneck we have is that, when there is a vaccine available, it will take some time to produce enough doses. What discussions has the Secretary of State had with vaccine manufacturers to ensure that there is enough mothballed capacity in the vaccine manufacturing industry in Europe and across the world to ensure that we get enough doses quickly enough when the vaccine is developed?

Alan Johnson: My hon. Friend raises a crucial point. That was an essential element of our negotiation of the advance supply agreement. We have the agreement with two companies: Baxter’s and GSK. Part of that is to ensure that we get the proper level of supply, and to ensure that, in the event of an outbreak of a pandemic, the country that the vaccine is manufactured in ensures that it reaches this country and is not prevented from doing so by measures taken in the country of production. That is why we have insisted that the vaccine must be manufactured in the European Union and why we have
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insisted on a clause stating that either the country of manufacture must have an agreement for sufficient supplies to the host country or that the companies must make that country aware of the agreement with this country. That is as far as we can go to ensure that we have the proper measures. The fact that we have the advance supply agreements in place—only two or three countries have similar agreements, so we are one of the first—means that we are better placed than most other countries to deal with the situation.

Mr. Nigel Evans (Ribble Valley) (Con): I congratulate the Secretary of State for Health on coming to the Chamber to make a statement. Perhaps he could have a word with his chum the Secretary of State for Transport to tell her that that there is nothing to be frightened of and that perhaps she should give it a go now and again.

One group that would clearly be under threat from an influenza pandemic is elderly people and those who are already infirm. Can the Secretary of State give any guidance on what advice would be given to people to be “good neighbours”? In rural areas, such as the area where I live, there tends to be a good neighbourhood policy in any event, particularly in relation to elderly people and those who live alone. One of the loneliest places, from my experience, is a city with a population of millions. People may live in a block of flats but still not talk to anybody on a day-to-day basis. Perhaps advice could be given that, particularly in the lead-up to what could be an outbreak of a flu pandemic, people should be good neighbours, look more carefully at people who live around them, and provide guidance and lifts to pharmacies or GPs.

Alan Johnson: The hon. Gentleman raises an important point, and guidance is an essential element. We are saying that if a person has any symptoms of the flu, they should go home. For the vast majority of the population, a flu pandemic will mean a couple of days in bed, and then they will be fine. The essential thing is that they do not spread the disease, so we advise them to stay at home.

We use the terminology “a flu friend”. A person with symptoms should not go to the pharmacy to collect their drugs, as they are likely to spread the illness. They should stay at home, and a friend, member of the family or colleague will go to the pharmacy for them, collect the antiviral, which is taken in tablet form, and take it home to them.

One of the many reasons that I am proud of this country is that there is still a community spirit. We saw it in the floods, and we see it every time there is an emergency. People are good at ensuring that they do as much for their community as possible. There can be a problem with ensuring that proper advice is given to people in isolated rural communities, who sometimes do not see a human face from one week to the next. We have to make sure that if they do not have relatives or friends nearby, someone is there and is responsible for ensuring that they receive the proper antiviral.

Paddy Tipping (Sherwood) (Lab): The Secretary of State has made it clear that there is no chance of people catching avian flu from eating poultry, provided that it is properly prepared and cooked. Given that this is an
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important time for the poultry industry, will he work with his colleagues in the Department for Environment, Food and Rural Affairs and with the industry to promote that message in the run-up to Christmas?

Alan Johnson: I will do that, but I am absolutely sure that my right hon. Friend the Secretary of State for Environment, Food and Rural Affairs needs no reminding. I have heard him make the point absolutely clear. It is essential that people are reassured that there is absolutely no danger from eating turkey—provided, of course, that it is cooked properly. If it is not, there would be a danger in any circumstances.

Mr. Roger Williams (Brecon and Radnorshire) (LD): As has been said, effective pre- and post-pandemic vaccinations are likely to be the most important tools for limiting the severity of an outbreak. The speed at which vaccines are developed is very important. It depends greatly on international surveillance to identify any emerging pandemic, including perhaps in less developed countries that do not have the facilities. What support are our Government giving to worldwide surveillance, so that we can identify any potential pandemic?

Alan Johnson: We are completely supporting the World Health Organisation’s attempts to ensure that that takes place. I have announced the extra £2 million that we are providing to ensure vaccination in developing countries. We are better placed than we were when previous pandemics broke out, as there is closer collaboration with other countries and better communications. That can mean that the pandemic spreads more widely, more quickly, so it is a double-edged sword. Surveillance, the necessity of concentrating on tackling an outbreak wherever it is in the world, and ensuring that the outbreak is an epidemic, not a pandemic, are central features of trying to protect the British public.

Martin Horwood (Cheltenham) (LD): I declare a personal interest, as my wife is a director of public health. I first questioned the attack and fatality rates in the Department’s assumptions last July, so I very much welcome a fresh look at those assumptions. Why is the Government’s worst-case fatality rate still only 2.5 per cent., given that among humans catching the avian variant the fatality rate is in excess of 50 per cent., and given that the Department has accepted that there are no comparable statistics for the precursors of earlier epidemics? Secondly, will the Secretary of State work with Ministers in the Department for International Development to increase production capacity in south-east Asia for pre-pandemic antiviral treatment, which might help to suppress an outbreak at source and increase global capacity for antiviral production?


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