Select Committee on Science and Technology Sixth Report


ACF    Academic Clinical Fellowship
AEDS    Atopic Eczema/Dermatitis Syndrome
AIDS    Autoimmune Deficiency Syndrome
ALSPAC    Avon Longitudinal Study of Parents And Children
ARIA    Allergic Rhinitis and its Impact on Asthma
ASA    Advertising Standards Authority
BBSRC    Biotechnology and Biological Sciences Research Council
BCAP    Broadcast Committee of Advertising Practice
BOHRF    British Occupational Health Research Foundation
BRC    British Retail Consortium
BSACI    British Society for Allergy and Clinical Immunology
CAP    Committee of Advertising Practice
CIEH    Chartered Institute of Environmental Health
CL    Clinical Lectureship
COMEAP    Committee on the Medical Effects of Air Pollutants
COSHH    Control of Substances Hazardous to Health 2002 (as amended) Regulations
COT    Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment
CSM    Committee on Safety of Medicines
DCLG    Department for Communities and Local Government
Defra    Department for Environment, Food and Rural Affairs
DEP    Diesel Exhaust Particle
DfES    Department for Education and Skills
DH    Department of Health
DIN    Doctors Independent Network
DWP    Department for Work and Pensions
EAA    Extrinsic Allergic Alveolitis
EAACI    European Academy of Allergology and Clinical Immunology
ECRHS    European Community Respiratory Health Survey
EFA    European Federation of Allergy
ELSPAC    European Longitudinal Study of Pregnancy And Childhood
ENT    Ear, Nose and Throat
EU    European Union
FSA    Food Standards Agency
GAIN    GA2LEN Anaphylaxis Initiative
GA2LEN    Global Allergy and Asthma European Network
GP    General Practitioner
GPRD    General Practice Research Database
GPwSI    General Practitioners with a Special Interest
GSK    GlaxoSmithKline
HIV    Human Immunodeficiency Virus
HPA    Health Protection Agency
HSE    Health and Safety Executive
IFR    Institute of Food Research
IIDB    Industrial Injuries Disablement Benefit
ISAAC    International Study of Asthma and Allergies in Childhood
IVD    in vitro Diagnostic Device
LACORS    Local Authorities Coordinators Of Regulatory Services
LEAP    Learning Early About Peanut allergy
MCS    Multiple Chemical Sensitivity
MHRA    Medicines and Healthcare products Regulatory Agency
MRC    Medical Research Council
NHS    National Health Service
NICE    National Institute for Health and Clinical Excellence
NO2    Nitrogen Dioxide
O3    Ozone
OSCHR    Office for Strategic Coordination of Health Research
OUH    Odense University Hospital
PAH    Polycyclic Aromatic Hydrocarbon
PALM    Pollen Associated Lipid Mediator
PCT    Primary Care Trust
PPD    Para-Phenylenediamine
RCGP WRS    Royal College of General Practitioners Weekly Returns Service
REACH    Registration, Evaluation, Authorisation and Restriction of Chemicals
RIDDOR    Reporting of Injuries, Diseases and Dangerous Occurrences Regulations 1995
RPSGB    Royal Pharmaceutical Society of Great Britain
SNOMED-CT    Systemized Nomenclature of Medicine classification system
SO2    Sulphur Dioxide
THOR    The Health and Occupation Reporting network
UK    United Kingdom
VOC    Volatile Organic Compound
WHO    World Health Organization
Adrenaline    A "fight or flight" hormone released from the adrenal glands when danger threatens. Used to treat anaphylaxis because it reverses the effects of histamine
Allergen    A substance which causes an allergic reaction
Allergy    An exaggerated, adverse reaction of the immune system to an external agent
Alveolus (pl. alveoli)    Spherical outcroppings at the ends of the respiratory bronchioles which are the primary sites of gas exchange with the blood
Anaphylaxis    An acute hypersensitivity reaction, often due to an allergy, in which there is a massive release of histamine throughout the body
Antibody    A protein produced by the immune system which binds in a "lock and key" fashion to a specific antigen (or allergen)
Antigen    A substance which produces an immune response (involving antibody production)
Antihistamine    A drug which antagonises the actions of histamine
Atopy    An atopic individual has the hereditary predisposition to produce IgE antibodies against common allergens
Autoimmune    An immune response against an individual's own antigens
Bronchiole    A small branch of the windpipe which conveys air to and from the lungs
Bronchus (pl. bronchi)    A large branch of the windpipe which conveys air to and from the lungs
Coeliac disease    A disease of the bowel that is caused by an allergy to gluten
Corticosteroid    An agent with potent anti-inflammatory properties
EPIDERM project    A scheme run by The Health and Occupation Reporting network to monitor the prevalence of occupational skin disorders
Hypersensitivity    An abnormal sensitivity to a stimulus. Often used specifically to describe an exaggerated immune response to an external substance
Hypoallergenic    A substance with a low potential to cause allergy
IgE    A class of antibodies produced in atopic individuals, which binds to mast cells and basophils (a type of white blood cell) and initiates an allergic reaction after interaction with a specific allergen
IgG    A class of antibodies produced as part of the normal immune response to a wide variety of external substances including micro-organisms and foods
Immunotherapy    The administration, over time, of increasing doses of an allergen to which a person is sensitive, in order to desensitise the allergic individual
Intolerance    An abnormal response to an external substance (such as food) which does not involve the immune system
Mast cell    A cell which is present in virtually all tissues which contains granules packed with histamine and other agents. It is activated by IgE and allergen during an allergic reaction
Polymorphism    A naturally occurring variation between genetic sequences of different individuals
Prophylactic    An agent which protects or prevents
SWORD    Surveillance of Work-related and Occupational Respiratory Disease; a scheme run by The Health and Occupation Reporting network to monitor the prevalence of occupational respiratory disorders
T helper 1 (Th1) cell    A type of immune cell involved in autoimmune disease and in killing certain intracellular organisms
T helper 2 (Th2) cell    A type of immune cell involved in atopic allergic disease and certain parasitic infections
Translational research    The clinical application of scientific, laboratory based, medical research. Often referred to as "bench to bedside" research

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